NAD+: The Molecule Behind Cellular Energy and Longevity
NAD+ is the coenzyme behind every cell's energy production. Its decline is a key driver of aging — and therapy can replenish it.
What is NAD+?
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme present in every living cell. It powers mitochondrial energy production, DNA repair, and the activity of sirtuins — proteins that regulate cellular aging.
Levels decline with age. By age 50, NAD+ is roughly half of what it was at 20.
Why NAD+ matters for aging
Lower NAD+ means less efficient mitochondria, slower DNA repair, and reduced sirtuin activity. The downstream effects: lower energy, slower recovery, cognitive fog, and accelerated biological aging.
Restoring NAD+ supports the underlying biology, not just symptoms.
How NAD+ therapy works
Hypergevity offers NAD+ as an injectable program and a nasal spray. Both deliver bioavailable NAD+ that bypasses the gut. Dosing is titrated to tolerance.
Many patients also use precursors like NMN or NR alongside lifestyle protocols (sleep, training, fasting) to maximize benefit.
What patients report
Common reports include sharper mental clarity, more stable energy through the day, better workout recovery, and improved sleep quality. Effects usually appear within 2–4 weeks of consistent dosing.
Frequently asked questions
Is NAD+ therapy safe?+
Yes, when administered under medical supervision. Side effects are typically limited to mild flushing or injection-site reaction.
How often do I dose NAD+?+
Protocols vary. Many patients dose 2–5 times per week during loading and then taper to maintenance.
Does NAD+ reverse biological age?+
Animal and early human data are promising. NAD+ restoration is considered a foundational longevity intervention by many researchers.
Injection vs nasal spray — which is better?+
Injection delivers higher and more predictable doses. Nasal spray is convenient and works well for maintenance.
How much does it cost?+
NAD+ programs at Hypergevity start at $199/month inclusive of provider oversight.
Medical Disclaimer.HYPERGEVITY provides telehealth services through independently owned and operated U.S. licensed medical practices. All prescriptions are at provider discretion based on individual medical evaluation. Not all treatments are appropriate for all patients. Results may vary. Information on this site is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.